TBC1D4 Polyclonal Antibody | G-AB-01874

TBC1D4 Polyclonal Antibody | G-AB-01874 | Gentaur Antibodies

Overview: TBC1 domain family member 4 (TBC1D4) , also designated AS160, can be insulin- and/or AKT1-induced. Insulin-stimulated phosphorylation is required for GLUT4 translocation. TBC1D4 may play a role as a GTPase activating protein for proteins in the Rab family. It is expressed primarily in skeletal muscle and heart, as well as spleen, lymph node and leukocytes. Defects in the TBC1D4 gene may cause atopic dermatitis (AD) , sometimes referred to as eczema, an atopic chronic skin disease. The skin of affected individuals reacts to irritants or allergens and becomes red, flaky and itchy. The skin is also more vulnerable to inflammations, and symptoms can grow or disappear over time.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: Acrg embryonic lethality (mouse) minimal region ortholog, Acrg embryonic lethality minimal region ortholog, Acrg embryonic lethality mouse minimal region ortholog, Akt substrate of 160 kDa, AS 160, AS160, BUB2, CDC16, KIAA0603, NIDDM5, TBC (Tre 2 BUB2 CDC16) domain containing protein, TBC Tre 2 BUB2 CDC16 domain containing protein, TBC1 D4, TBC1 domain family member 4, Tbc1d4, TBCD4, Tre-2

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_055647

Clonality: Polyclonal

Immunogen: Synthetic peptide of human TBC1D4

Clone #:

Conjugation: Unconjugated

Swissprot: O60343

Santa Cruz: sc-47470/sc-135256

Calculated MW: 147 kDa

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:30-1:150

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TBC1D4 Polyclonal Antibody DataSheet