TBP Polyclonal Antibody | G-AB-12705
- 3 to 5 Working Days
- Human, Mouse, Rat
TBP Polyclonal Antibody | G-AB-12705 | Gentaur Antibodies
Overview: The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. This antibody detects human TBP (~40 kDa) and mouse/rat Tbp (~35 kDa) .
Category Type: Control Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: GTF2D, GTF2D1, HDL4, SCA17, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, TBP, TFIID, Transcription initiation factor TFIID TBP subunit
Reactivity: Human, Mouse, Rat
Gene ID: 6908
Immunogen: Synthetic peptide of Human TATA-box-binding protein
Calculated MW: 38 kDa
Observed MW: 38 kDa
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification method: Antigen Affinity Purification
Dilution: WB 1:4000-1:6000
Storage: Store at -20℃. Avoid freeze / thaw cycles.