TEK Polyclonal Antibody | G-AB-11569
- 3 to 5 Working Days
- Human, Mouse, Rat
TEK Polyclonal Antibody | G-AB-11569 | Gentaur Antibodies
Overview: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF) -like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells
Synonyms: TEK, CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1, Tie2
Reactivity: Human, Mouse, Rat
Gene ID: 7010
Immunogen: Recombinant fusion protein of human TEK (NP_000450.2) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.