TGFB1 Polyclonal Antibody | G-AB-08936

TGFB1 Polyclonal Antibody | G-AB-08936 | Gentaur Antibodies

Overview: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction, Stem cells

Synonyms: TGFB1, CED, DPD1, LAP, TGFB, TGFbeta, TGF-β

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 7040

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human TGFB1 (NP_000651.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: P01137

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TGFB1 Polyclonal Antibody DataSheet