THRB Polyclonal Antibody | G-AB-09209
Gentaur Antibodies
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Gentaur Antibodies
THRB Polyclonal Antibody | G-AB-09209
- SKU:
- G-AB-09209
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
THRB Polyclonal Antibody | G-AB-09209 | Gentaur Antibodies
Overview: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR) , a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4) , with normal or slightly elevated thyroid stimulating hormone (TSH) . Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
Category Type: Polyclonal Antibody
Research Areas:
Synonyms: THRB, C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 7068
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human THRB (NP_000452.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: P10828
Santa Cruz:
Calculated MW: 52 kDa/54 kDa
Observed MW: 53 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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