TIMP2 Polyclonal Antibody | G-AB-00363

TIMP2 Polyclonal Antibody | G-AB-00363 | Gentaur Antibodies

Overview: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Category Type: Polyclonal Antibody

Research Areas: Cardiovascular, Signal Transduction, Cancer, Cell Biology, Cardiovascular

Synonyms: CSC 21K, Metalloproteinase inhibitor 2, Metalloproteinase inhibitor 2 precursor, TIMP 2, TIMP metallopeptidase inhibitor 2, TIMP2, Tissue inhibitor of metalloproteinases 2

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 7077

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Human Metalloproteinase inhibitor 2 protein

Clone #:

Conjugation: Unconjugated

Swissprot: P16035

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Purification method: Antigen Affinity Purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TIMP2 Polyclonal Antibody DataSheet