TIMP2 Polyclonal Antibody | G-AB-09098

TIMP2 Polyclonal Antibody | G-AB-09098 | Gentaur Antibodies

Overview: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Synonyms: TIMP2, CSC-21K, DDC8

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 7077

Accession #:

Clonality:

Immunogen: A synthetic peptide of human TIMP2 (NP_003246.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P16035

Santa Cruz:

Calculated MW: 24 kDa

Observed MW: 26 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TIMP2 Polyclonal Antibody DataSheet