TIRAP Polyclonal Antibody | G-AB-03406
Gentaur Antibodies
- SKU:
- G-AB-03406
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
TIRAP Polyclonal Antibody | G-AB-03406 | Gentaur Antibodies
Overview: The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs) , which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for Signal Transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Immunology, Signal Transduction
Synonyms: Adapter protein wyatt, FLJ42305, MAL, MyD88 adapter like protein, TIR domain containing adapter protein, Toll interleukin 1 receptor (TIR) domain containing adaptor protein, Toll interleukin 1 receptor domain containing adapter protein, Toll like receptor adaptor protein, Wyatt
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC032474
Clonality: Polyclonal
Immunogen: Full length fusion protein
Clone #:
Conjugation: Unconjugated
Swissprot: P58753
Santa Cruz: sc-19950/sc-19952/sc-31308/sc-31309/sc-28822
Calculated MW:
Observed MW:
Concentration: 0.5 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:25-100, ELISA 1:2000-5000
Storage: Store at -20°C. Avoid freeze / thaw cycles.