TIRAP Polyclonal Antibody | G-AB-09843

TIRAP Polyclonal Antibody | G-AB-09843 | Gentaur Antibodies

Overview: The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs) , which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for Signal Transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Immunology, Signal Transduction

Synonyms: TIRAP, BACTS1, Mal, MyD88-2, wyatt

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 114609

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human TIRAP (NP_001034750.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P58753

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TIRAP Polyclonal Antibody DataSheet