TIRAP Polyclonal Antibody | G-AB-03406

TIRAP Polyclonal Antibody | G-AB-03406 | Gentaur Antibodies

Overview: The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs) , which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for Signal Transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Immunology, Signal Transduction

Synonyms: Adapter protein wyatt, FLJ42305, MAL, MyD88 adapter like protein, TIR domain containing adapter protein, Toll interleukin 1 receptor (TIR) domain containing adaptor protein, Toll interleukin 1 receptor domain containing adapter protein, Toll like receptor adaptor protein, Wyatt

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC032474

Clonality: Polyclonal

Immunogen: Full length fusion protein

Clone #:

Conjugation: Unconjugated

Swissprot: P58753

Santa Cruz: sc-19950/sc-19952/sc-31308/sc-31309/sc-28822

Calculated MW:

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:25-100, ELISA 1:2000-5000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TIRAP Polyclonal Antibody DataSheet