TJP1 Polyclonal Antibody | G-AB-06055

TJP1 Polyclonal Antibody | G-AB-06055 | Gentaur Antibodies

Overview: Tight junction (or zonula occludens) form the continuous intercellular barrier between epithelial and endothelial cells, which is required to separate tissue spaces and regulate selective movement of solutes across the epithelium and endothelium . ZO-1 (also known as TJP1) is a peripheral membrane phosphoprotein located on the cytoplasmic face and is expressed in tight junctions of both epithelial and endothelial cells . It binds the transmembrane proteins occludin and the claudins linking them to cytoskeletal actin . ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase homologs (MAGUKs) . It is a pivotal tight junction protein and may be involved in signalling mechanisms regulating cell proliferation and differentiation .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Tags & Cell Markers

Synonyms: Tight junction protein 1, Tight junction protein ZO-1, Tight junction protein ZO1, TJP1, zo-1, Zo1, ZO1, Zona occludens 1, Zona occludens 1 protein, Zona occludens protein 1, Zonula occludens 1 protein, Zonula occludens protein 1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP003248

Clonality: Polyclonal

Immunogen: Synthetic peptide of human TJP1

Clone #:

Conjugation: Unconjugated

Swissprot: Q07157

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TJP1 Polyclonal Antibody DataSheet