TLR2 Polyclonal Antibody | G-AB-10115

TLR2 Polyclonal Antibody | G-AB-10115 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs) . Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Immunology, Microbiology, Signal Transduction

Synonyms: CD282, TIL4, TLR2

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 7097

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human TLR2 (NP_003255.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O60603

Santa Cruz:

Calculated MW: 89 kDa

Observed MW: 100 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TLR2 Polyclonal Antibody DataSheet