TLR9 Polyclonal Antibody | G-AB-08753

TLR9 Polyclonal Antibody | G-AB-08753 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Category Type: Polyclonal Antibody

Research Areas: Immunology, Signal Transduction

Synonyms: TLR9, CD289

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 54106

Accession #:

Clonality:

Immunogen: A synthetic peptide of human TLR9 (NP_059138.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NR96

Santa Cruz:

Calculated MW: 109 kDa/114 kDa/115 kDa/118 kDa

Observed MW: 125 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TLR9 Polyclonal Antibody DataSheet