TMEM43 Polyclonal Antibody | G-AB-12243
Gentaur Antibodies
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Gentaur Antibodies
TMEM43 Polyclonal Antibody | G-AB-12243
- SKU:
- G-AB-12243
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
TMEM43 Polyclonal Antibody | G-AB-12243 | Gentaur Antibodies
Overview: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5) , also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5) . Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor) , which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction, Tags & Cell Markers
Synonyms: TMEM43, ARVC5, ARVD5, EDMD7, LUMA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 79188
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human TMEM43 (NP_077310.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q9BTV4
Santa Cruz:
Calculated MW: 44 kDa
Observed MW: 45 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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