TNFR2 Polyclonal Antibody | G-AB-07460
Gentaur Antibodies
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Gentaur Antibodies
TNFR2 Polyclonal Antibody | G-AB-07460
- SKU:
- G-AB-07460
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
TNFR2 Polyclonal Antibody | G-AB-07460 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Cardiovascular, Immunology, Neuroscience, Signal Transduction
Synonyms: CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR, TNF Receptor II, TNFRSF1B
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 7133
Accession #:
Clonality:
Immunogen: A synthetic peptide of human TNFRSF1B
Clone #:
Conjugation: Unconjugated
Swissprot: P20333
Santa Cruz:
Calculated MW: 28 kDa/48 kDa
Observed MW: 64 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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