TNK2 Polyclonal Antibody | G-AB-10100

TNK2 Polyclonal Antibody | G-AB-10100 | Gentaur Antibodies

Overview: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP) -stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation Signal Transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: TNK2, ACK, ACK-1, ACK1, p21cdc42Hs

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 10188

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human TNK2 (NP_001010938.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q07912

Santa Cruz:

Calculated MW: 60 kDa/114 kDa/119 kDa

Observed MW: 115 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TNK2 Polyclonal Antibody DataSheet