TNNT1 Polyclonal Antibody | G-AB-04612

TNNT1 Polyclonal Antibody | G-AB-04612 | Gentaur Antibodies

Overview: This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: ANM, MGC104241, NEM5, Skeletal, Slow, slow skeletal muscle, Slow skeletal muscle troponin T, sTnT, Tnnt1, TNNT1, TNT, TnTs, Troponin T, Troponin T slow skeletal muscle, Troponin T type 1 (skeletal slow) , troponin T1 skeletal slow, Troponin T1, slow skeletal type

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC010963

Clonality: Polyclonal

Immunogen: Fusion protein of human TNNT1

Clone #:

Conjugation: Unconjugated

Swissprot: P13805

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.32 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TNNT1 Polyclonal Antibody DataSheet