TPM1 Polyclonal Antibody | G-AB-02147

TPM1 Polyclonal Antibody | G-AB-02147 | Gentaur Antibodies

Overview: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction

Synonyms: AA986836, AI854628, Alpha tropomyosin, alpha-TM, Alpha-tropomyosin, C15orf13, cardiomyopathy, hypertrophic 3, CMD1Y, CMH3, HTM alpha, HTM-alpha, OTTHUMP00000163688, sarcomeric tropomyosin kappa, TM2, Tmpa, TMSA, Tpm-1, TPM1, TPM1, tropomyosin 1 (alpha) , tropomyosin 1 (alpha) isoform 1, tropomyosin 1 (alpha) isoform 2, tropomyosin 1 (alpha) isoform 3, tropomyosin 1 (alpha) isoform 4, tropomyosin 1 (alpha) isoform 5, tropomyosin 1 (alpha) isoform 6, tropomyosin 1 (alpha) isoform 7, Tropomyosin 1, Tropomyosin alpha 1 chain, Tropomyosin alpha-1 chain, Tropomyosin, skeletal muscle alpha, Tropomyosin-1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC007433

Clonality: Polyclonal

Immunogen: Recombinant protein of human TPM1

Clone #:

Conjugation: Unconjugated

Swissprot: P09493

Santa Cruz: sc-32514/sc-32516/sc-21806/sc-21807/sc-18174/sc-28543

Calculated MW: 33 kDa

Observed MW:

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TPM1 Polyclonal Antibody DataSheet