TPM1 Polyclonal Antibody | G-AB-07572

TPM1 Polyclonal Antibody | G-AB-07572 | Gentaur Antibodies

Overview: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction

Synonyms: TPM1, C15orf13, CMD1Y, CMH3, HEL-S-265, HTM-alpha, LVNC9, TMSA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 7168

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human TPM1 (NP_001018008.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P09493

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TPM1 Polyclonal Antibody DataSheet