TPMT Polyclonal Antibody | G-AB-08556
Gentaur Antibodies
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Gentaur Antibodies
TPMT Polyclonal Antibody | G-AB-08556
- SKU:
- G-AB-08556
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
TPMT Polyclonal Antibody | G-AB-08556 | Gentaur Antibodies
Overview: This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Signal Transduction
Synonyms: TPMT, TPMTD
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 7172
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human TPMT (NP_000358.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P51580
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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