TTR Monoclonal Antibody | G-AB-05726
- 3 to 5 Working Days
TTR Monoclonal Antibody | G-AB-05726 | Gentaur Antibodies
Overview: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
Category Type: Monoclonal Antibody
Research Areas: Cancer, Cardiovascular, Neuroscience
Synonyms: Amyloid polyneuropathy, Amyloidosis I, ATTR, Carpal tunnel syndrome 1, CTS, CTS1, Dysprealbuminemic euthyroidal hyperthyroxinemia, Dystransthyretinemic hyperthyroxinemia, Epididymis luminal protein 111, HEL111, HsT2651, PALB, Prealbumin amyloidosis type I, Prealbumin, Prealbumin Thyroxine-binding, Senile systemic amyloidosis, TBPA, Thyroxine binding prealbumin, Transthyretin, TTHY, TTR, TTR protein
Immunogen: Recombinant Protein of TTR
Clone #: Clone:2B12
Observed MW: 16 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification method: Protein A purification
Application: WB, IHC-p
Dilution: WB 1:500-2000, IHC 1:50-300
Storage: Store at -20°C. Avoid freeze / thaw cycles.