UGT1A4 Polyclonal Antibody | G-AB-10707

UGT1A4 Polyclonal Antibody | G-AB-10707 | Gentaur Antibodies

Overview: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: UGT1A4, HUG-BR2, UDPGT, UDPGT 1-4, UGT-1D, UGT1-04, UGT1.4, UGT1A4S, UGT1D, UDPGT1-4

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 54657

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human UGT1A4 (NP_009051.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P22310

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

UGT1A4 Polyclonal Antibody DataSheet