UMOD Polyclonal Antibody | G-AB-00192
Gentaur Antibodies
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Gentaur Antibodies
UMOD Polyclonal Antibody | G-AB-00192
- SKU:
- G-AB-00192
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
UMOD Polyclonal Antibody | G-AB-00192 | Gentaur Antibodies
Overview: The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2) , glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI) , and familial juvenile hyperuricemic nephropathy (FJHN) . Alternative splicing of this gene results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology
Synonyms: ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, medullary cystic kidney disease 2 (autosomal dominant) , Tamm Horsfall glycoprotein, Tamm Horsfall urinary glycoprotein, Tamm-Horsfall urinary glycoprotein, THGP, THP, Umod, Urehd1, urehr4, UROM_HUMAN, uromodulin (uromucoid, Tamm-Horsfall glycoprotein) , Uromodulin
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #:
Clonality: Polyclonal
Immunogen: Recombinant Human Uromodulin protien
Clone #:
Conjugation: Unconjugated
Swissprot: P07911
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 2 mg/mL
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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