UMPS Polyclonal Antibody | G-AB-10688

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€183.12 - €390.60
SKU:
G-AB-10688
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human
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UMPS Polyclonal Antibody | G-AB-10688 | Gentaur Antibodies

Overview: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling, Metabolism

Synonyms: UMPS, OPRT

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 7372

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human UMPS (NP_000364.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P11172

Santa Cruz:

Calculated MW: 22 kDa/33 kDa/42 kDa/52 kDa

Observed MW: 56 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

UMPS Polyclonal Antibody DataSheet