UPF2 Polyclonal Antibody | G-AB-08220

UPF2 Polyclonal Antibody | G-AB-08220 | Gentaur Antibodies

Overview: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD) . When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: UPF2, HUPF2, RENT2, smg-3

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 26019

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human UPF2 (NP_542166.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9HAU5

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

UPF2 Polyclonal Antibody DataSheet