XRCC4 Monoclonal Antibody | G-AB-05551
Gentaur Antibodies
- SKU:
- G-AB-05551
- Availability:
- 3 to 5 Working Days
- Host:
- Mouse
- Reactivity:
- Human
XRCC4 Monoclonal Antibody | G-AB-05551 | Gentaur Antibodies
Overview: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V (D) J recombination. Binds to DNA and to DNA ligase IV (LIG4) . The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Category Type: Monoclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: DNA double strand break repair and V (D) J recombination protein XRCC4, DNA repair protein XRCC4, SSMED, X ray repair complementing defective repair in Chinese hamster cells 4, X ray repair cross complementing 4, X ray repair cross complementing protein 4, X-ray repair cross-complementing protein 4, XRCC 4, XRCC4, XRCC4
Reactivity: Human
Host: Mouse
Isotype: IgG
Gene ID:
Accession #:
Clonality: Monoclonal
Immunogen: Synthetic Peptide
Clone #: Clone:8K2
Conjugation: Unconjugated
Swissprot: Q13426
Santa Cruz: sc-136124/sc-365055/sc-365118
Calculated MW: 38 kDa
Observed MW: 38 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification method: Protein A purification
Application: WB, IHC-p, IF, IP
Dilution: WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
Storage: Store at -20°C. Avoid freeze / thaw cycles.