XRCC5 Polyclonal Antibody | G-AB-08189
Gentaur Antibodies
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Gentaur Antibodies
XRCC5 Polyclonal Antibody | G-AB-08189
- SKU:
- G-AB-08189
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
XRCC5 Polyclonal Antibody | G-AB-08189 | Gentaur Antibodies
Overview: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: XRCC5, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 7520
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human XRCC5 (NP_066964.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P13010
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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