YBX1 Polyclonal Antibody | G-AB-07066
Gentaur Antibodies
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Gentaur Antibodies
YBX1 Polyclonal Antibody | G-AB-07066
- SKU:
- G-AB-07066
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
YBX1 Polyclonal Antibody | G-AB-07066 | Gentaur Antibodies
Overview: This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3') , such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro) .
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells, Tags & Cell Markers
Synonyms: BP 8, CBF-A, CCAAT binding transcription factor I subunit A, CCAAT-binding transcription factor I subunit A, CSDA2, CSDB, DBPB, DNA binding protein B, DNA-binding protein B, EFI-A, Enhancer factor I subunit A, MDR NF1, MGC104858, MGC110976, MGC117250, NSEP 1, NSEP1, Nuclease sensitive element binding protein 1, Nuclease-sensitive element-binding protein 1, p50, Q15905, Y-box binding protein 1, Y-box transcription factor, Y-box-binding protein 1, YB 1, YB-1, YBOX1, YBX 1, ybx1
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP004550
Clonality: Polyclonal
Immunogen: Synthetic peptide of human YBX1
Clone #:
Conjugation: Unconjugated
Swissprot: P67809
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 0.6 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: IHC, ELISA
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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