ZFAND5 Polyclonal Antibody | G-AB-03964

ZFAND5 Polyclonal Antibody | G-AB-03964 | Gentaur Antibodies

Overview: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF) , IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: AN1-type zinc finger protein 5, ZA20D2, ZFAN5, Zfand5, ZFAND5A, zinc finger A20 domain containing 2, Zinc finger A20 domain containing protein 2, Zinc finger A20 domain-containing protein 2, zinc finger AN1 type domain 5, Zinc finger protein 216, ZNF216

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC011018

Clonality: Polyclonal

Immunogen: Full length fusion protein

Clone #:

Conjugation: Unconjugated

Swissprot: O76080

Santa Cruz:

Calculated MW: 23 kDa

Observed MW: Refer to figures

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ZFAND5 Polyclonal Antibody DataSheet