ZNF354A Polyclonal Antibody | G-AB-06229

ZNF354A Polyclonal Antibody | G-AB-06229 | Gentaur Antibodies

Overview: ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Krüppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the adult kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling, Neuroscience

Synonyms: EZNF, HKL1, HLK1, Homo sapiens zinc finger protein 354A, KID 1, KID1, Kidney, ischemia, and developmentally regulated protein 1, Renal transcription factor Kid 1, TCF-17, TCF17, Transcription factor 17, Z354A, Zinc finger protein 354A, Zinc finger protein eZNF, ZNF354A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC047105

Clonality: Polyclonal

Immunogen: Fusion protein of human ZNF354A

Clone #:

Conjugation: Unconjugated

Swissprot: O60765

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ZNF354A Polyclonal Antibody DataSheet