A2M Polyclonal Antibody | G-AB-09378
- 3 to 5 Working Days
A2M Polyclonal Antibody | G-AB-09378 | Gentaur Antibodies
Overview: The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Cardiovascular
Synonyms: A2M, A2MD, CPAMD5, FWP007, S863-7
Gene ID: 2
Immunogen: Recombinant fusion protein of human A2M (NP_000005.2) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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