AAK1 Polyclonal Antibody | G-AB-06098
- 3 to 5 Working Days
- Human, Mouse, Rat
AAK1 Polyclonal Antibody | G-AB-06098 | Gentaur Antibodies
Overview: Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Category Type: Polyclonal Antibody
Research Areas: Signal Transduction
Synonyms: AAK 1, Aak1, AAK1, Adaptor associated kinase 1, Adaptor-associated kinase 1, AP2 associated kinase 1, AP2 associated protein kinase 1, AP2-associated protein kinase 1, DKFZp686F03202, DKFZp686K16132, FLJ23712, FLJ25931, FLJ31060, FLJ42882, FLJ45252, KIAA1048, MGC138170, MGC164568, MGC164570
Reactivity: Human, Mouse, Rat
Accession #: BC002695
Immunogen: Fusion protein of human AAK1
Calculated MW: 104 kDa
Observed MW: Refer to figures
Concentration: 0.6 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: WB, ELISA
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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