AMACR Polyclonal Antibody | G-AB-07523

AMACR Polyclonal Antibody | G-AB-07523 | Gentaur Antibodies

Overview: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) - and (S) -stereoisomers. The conversion to the (S) -stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology, Metabolism, Signal Transduction

Synonyms: AMACR, AMACRD, CBAS4, P504S, RACE, RM

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 23600

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human AMACR (NP_976316.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UHK6

Santa Cruz:

Calculated MW: 22 kDa/25 kDa/42 kDa/43 kDa

Observed MW: 43 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

AMACR Polyclonal Antibody DataSheet