CASP10 Polyclonal Antibody | G-AB-01903

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CASP10 Polyclonal Antibody | G-AB-01903 | Gentaur Antibodies

Overview: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism

Synonyms: ALPS2, Apoptotic protease Mch-4, CASP 10, CASP-10, CASP10, CASPA, Caspase 10 apoptosis related cysteine peptidase, Caspase-10 subunit p12, FADD like ICE2, Fas associated death domain protein, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE 2, FLICE2, ICE like apoptotic protease 4, ICE-like apoptotic protease 4, Interleukin 1B converting enzyme 2, MCH 4

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC042844

Clonality: Polyclonal

Immunogen: Recombinant protein of human CASP10

Clone #:

Conjugation: Unconjugated

Swissprot: Q92851

Santa Cruz: sc-22184/sc-6184/sc-6186/sc-6185/sc-7955

Calculated MW:

Observed MW:

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CASP10 Polyclonal Antibody DataSheet