Cathepsin B Polyclonal Antibody | G-AB-00473

Cathepsin B Polyclonal Antibody | G-AB-00473 | Gentaur Antibodies

Overview: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP) . Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: Amyloid precursor protein secretase, APP secretase, APPS, CATB, Cathepsin B heavy chain, Cathepsin B1, CathepsinB, CPSB, CTSB, cysteine protease, OTTHUMP00000116009, OTTHUMP00000229510, OTTHUMP00000229511, OTTHUMP00000229512, OTTHUMP00000229514, OTTHUMP00000229515, OTTHUMP00000229516, Preprocathepsin B

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC010240

Clonality: Polyclonal

Immunogen: Recombinant protein of human CTSB

Clone #:

Conjugation: Unconjugated

Swissprot: P07858

Santa Cruz: sc-6493/sc-13985/sc-6490-R

Calculated MW:

Observed MW:

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:150-1:500

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Cathepsin B Polyclonal Antibody DataSheet