Cathepsin E Polyclonal Antibody | G-AB-00474

Cathepsin E Polyclonal Antibody | G-AB-00474 | Gentaur Antibodies

Overview: The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: CATE, CATE, Cathepsin E, Cathepsin E form II, CTSE, Erythrocyte membrane aspartic proteinase, Slow moving proteinase

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC042537

Clonality: Polyclonal

Immunogen: Recombinant protein of human CTSE

Clone #:

Conjugation: Unconjugated

Swissprot: P14091

Santa Cruz: sc-6508/sc-6509/sc-30055

Calculated MW: 43 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Cathepsin E Polyclonal Antibody DataSheet