CAV3 Polyclonal Antibody | G-AB-12030
- 3 to 5 Working Days
- Human, Mouse
CAV3 Polyclonal Antibody | G-AB-12030 | Gentaur Antibodies
Overview: This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C) , hyperCKemia or rippling muscle disease (RMD) . Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Metabolism, Developmental Biology, Signal Transduction, Tags & Cell Markers
Synonyms: CAV3, LGMD1C, LQT9, VIP-21, VIP21
Reactivity: Human, Mouse
Gene ID: 859
Immunogen: Recombinant fusion protein of human CAV3 (NP_001225.1) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.