CBLB Polyclonal Antibody | G-AB-09887
Gentaur Antibodies
- SKU:
- G-AB-09887
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
CBLB Polyclonal Antibody | G-AB-09887 | Gentaur Antibodies
Overview: This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Immunology
Synonyms: CBLB, Cbl-b, Nbla00127, RNF56
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 868
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human CBLB (NP_733762.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q13191
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.