CBLB Polyclonal Antibody | G-AB-09887

CBLB Polyclonal Antibody | G-AB-09887 | Gentaur Antibodies

Overview: This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Immunology

Synonyms: CBLB, Cbl-b, Nbla00127, RNF56

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 868

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CBLB (NP_733762.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13191

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CBLB Polyclonal Antibody DataSheet