CD284 Polyclonal Antibody | G-AB-05953
- 3 to 5 Working Days
- Human, Mouse
CD284 Polyclonal Antibody | G-AB-05953 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in Signal Transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Immunology, Microbiology
Synonyms: ARMD10, CD284, CD284 antigen, Homolog of Drosophila toll, hToll, TLR 4, TLR4, TLR4, TOLL, Toll like receptor 4, Toll-like receptor 4
Reactivity: Human, Mouse
Immunogen: Synthesized peptide derived from the Internal region of human CD284.
Calculated MW: 96 kDa
Observed MW: 95 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification method: Affinity purification
Application: WB, IHC-p, IF, ELISA
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:40000
Storage: Store at -20°C. Avoid freeze / thaw cycles.