CD46 Polyclonal Antibody | G-AB-08295

CD46 Polyclonal Antibody | G-AB-08295 | Gentaur Antibodies

Overview: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: AHUS2, MCP, MIC10, TLX, TRA2.10, CD46

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 4179

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CD46 (NP_722548.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P15529

Santa Cruz:

Calculated MW: 36 kDa/39 kDa/40 kDa/41 kDa/42 kDa/43 kDa/44 kDa

Observed MW: 44 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CD46 Polyclonal Antibody DataSheet