CEMIP Polyclonal Antibody | G-AB-03881

CEMIP Polyclonal Antibody | G-AB-03881 | Gentaur Antibodies

Overview: Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT) , and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience

Synonyms: IR2155535, KIAA1199 protein, OTTHUMP00000185569, OTTHUMP00000195036, TMEM2L, Transmembrane protein 2 like

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP061159

Clonality: Polyclonal

Immunogen: Synthetic peptide of human CEMIP

Clone #:

Conjugation: Unconjugated

Swissprot: Q8WUJ3

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.68 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:100-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CEMIP Polyclonal Antibody DataSheet