CEP57 Polyclonal Antibody | G-AB-06322
Gentaur Antibodies
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Gentaur Antibodies
CEP57 Polyclonal Antibody | G-AB-06322
- SKU:
- G-AB-06322
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
CEP57 Polyclonal Antibody | G-AB-06322 | Gentaur Antibodies
Overview: This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2) , sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Category Type: Polyclonal Antibody
Research Areas: Signal Transduction, Stem cells
Synonyms: Centrosomal protein 57kDa, Centrosomal protein of 57 kDa, Cep57, Cep57 protein, CEP57, FGF2 interacting protein, FGF2-interacting protein, KIAA0092, MVA2, PIG8, Proliferation inducing protein 8, Testis specific protein 57, Testis-specific protein 57, Translokin, TSP57
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC039711
Clonality: Polyclonal
Immunogen: Full length fusion protein
Clone #:
Conjugation: Unconjugated
Swissprot: Q86XR8
Santa Cruz:
Calculated MW: 57 kDa
Observed MW: Refer to figures
Concentration: 0.4 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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