CRK Polyclonal Antibody | G-AB-09285
Gentaur Antibodies
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Gentaur Antibodies
CRK Polyclonal Antibody | G-AB-09285
- SKU:
- G-AB-09285
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
CRK Polyclonal Antibody | G-AB-09285 | Gentaur Antibodies
Overview: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction
Synonyms: CRK, CRKII, p38
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 1398
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human CRK (NP_058431.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: P46108
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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