CRK Polyclonal Antibody | G-AB-09285

CRK Polyclonal Antibody | G-AB-09285 | Gentaur Antibodies

Overview: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: CRK, CRKII, p38

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 1398

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CRK (NP_058431.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P46108

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CRK Polyclonal Antibody DataSheet