CYCS Polyclonal Antibody | G-AB-00170
- 3 to 5 Working Days
- Human, Bovine
CYCS Polyclonal Antibody | G-AB-00170 | Gentaur Antibodies
Overview: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction
Synonyms: Cytochrome C, Somatic, CYC, Cytochrome C, THC4, HCS.
Reactivity: Human, Bovine
Immunogen: Recombinant Human Cytochrome c protein
Calculated MW: 12 kDa
Observed MW: 12 kDa
Concentration: 2 mg/mL
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:1000-1:2000 IHC 1:100-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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It was very easy to use . I appreciated how quickly I got my results. I would recommend it.