CYCS Polyclonal Antibody | G-AB-00170

CYCS Polyclonal Antibody | G-AB-00170 | Gentaur Antibodies

Overview: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction

Synonyms: Cytochrome C, Somatic, CYC, Cytochrome C, THC4, HCS.

Reactivity: Human, Bovine

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Human Cytochrome c protein

Clone #:

Conjugation: Unconjugated

Swissprot: P99999

Santa Cruz:

Calculated MW: 12 kDa

Observed MW: 12 kDa

Concentration: 2 mg/mL

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:1000-1:2000 IHC 1:100-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CYCS Polyclonal Antibody DataSheet