DPM1 Polyclonal Antibody | G-AB-11851
- 3 to 5 Working Days
- Human, Mouse, Rat
DPM1 Polyclonal Antibody | G-AB-11851 | Gentaur Antibodies
Overview: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER) . Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Tags & Cell Markers
Synonyms: DPM1, CDGIE, MPDS
Reactivity: Human, Mouse, Rat
Gene ID: 8813
Immunogen: Recombinant fusion protein of human DPM1 (NP_003850.1) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.