DPM1 Polyclonal Antibody | G-AB-11851

DPM1 Polyclonal Antibody | G-AB-11851 | Gentaur Antibodies

Overview: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER) . Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Tags & Cell Markers

Synonyms: DPM1, CDGIE, MPDS

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8813

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DPM1 (NP_003850.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O60762

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DPM1 Polyclonal Antibody DataSheet