DSG1 Polyclonal Antibody | G-AB-12400
- 3 to 5 Working Days
- Human, Rat
DSG1 Polyclonal Antibody | G-AB-12400 | Gentaur Antibodies
Overview: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction
Synonyms: DSG1, CDHF4, DG1, DSG, EPKHE, EPKHIA, PPKS1, SPPK1
Reactivity: Human, Rat
Gene ID: 1828
Immunogen: Recombinant fusion protein of human DSG1 (NP_001933.2) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:50-1:100 IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.